Intermittent Fasting and Its Impact on Autophagy

Breaking News: Intermittent Fasting and Autophagy

Intermittent Fasting and Nutrient Impact

WEB Intermittent fasting (IF) encompasses eating patterns in which individuals go extended time periods (e.g., 16-48 hours) without consuming any food. This eating approach has gained prominence due to potential health benefits, including improved metabolic regulation and reduced risk of chronic diseases.

Dietary Changes and Circulating Nutrient Levels

WEB Changes in diet profoundly impact circulating nutrient levels in the plasma and the tumor microenvironment. The composition of nutrients available in these fluids influences cellular processes, including immune function and metabolism. Intermittent fasting alters nutrient availability, potentially affecting autophagy, a cellular recycling process crucial for maintaining cellular homeostasis.

Macroautophagy and its Role

WEB Macroautophagy (herein referred to as autophagy) is a conserved lysosomal degradation pathway for the degradation and recycling of cellular components. Autophagy plays a central role in maintaining cellular health by removing damaged organelles, proteins, and other cellular debris. It is also involved in regulating immune responses and cell death.